An increasing number of women face sterility due to cessation of normal ovarian function. This is a new method to treat their premature insufficiency.
Premature ovarian failure or loss of normal ovarian function means that the ovaries do not produce egg cells, they create fewer cells or are of poor quality. As a result of this condition, which affects one of 1,000 women between the ages of 15 and 29 and one in 100 women between the ages of 30 and 39, sterility occurs. Premature ovarian insufficiency may occur rapidly or, more often, over several years.
For the first time, in our clinic “Jevremova”, a unique program of regeneration of ovarian function with stem cells and growth factors was performed.
It’s not the same as menopause
As emphasized by prof. Dr. Aleksandar Ljubić from the General Hospital Medigroup, our eminent expert for IVF, premature ovarian insufficiency is sometimes associated with premature menopause, but these two conditions are not the same.
– Women who experience premature ovarian failure may have irregular or occasional cycles for years, and may remain in the second condition. Women who experience premature menopause have no cycles and cannot get pregnant naturally. Women who have a normal ovarian function of pituitary hormones during the menstrual cycle that affect the follicles in the ovaries to create mature eggs. It is customary to mature one cell a month. When it matures, the follicle sprays and the egg cell leaves the ovary. It then goes to the tubers where it is possible to fertilize, which can result in embryo implantation in the uterine mucous membrane or pregnancy. In premature ovarian failure, a small number of follicles respond to the pituitary signal that the release of the folliculated hormone has started, i.e. FSH. Follicles still exist but do not communicate and, therefore, do not enter the process of maturation of the egg cell. And if the follicles do not mature, menstruation becomes irregular or completely discontinued, and with it begins the atrophy of the uterus and ovaries – explains prof. dr Ljubić.
Why it’s useful
There are a number of methods that attempt to treat this disorder without adequate success. One of the new and unique therapeutic methods in our country, which has so far resulted, is the application of appropriate growth factors in the ovary, the so-called rejuvenation or ovarian regeneration.
– This is a multi-phase procedure, and it is carried out after a complete examination of possible patterns of omission of the ovary function, treatment of hereditary, hormonal and immunological factors – says our interlocutor.
The first phase involves the extraction of an adequate amount of blood, which depends on the patient’s constitution and the degree of oxygen deprivation, clinical picture and prognosis, as well as the desired composition of the factors that are injected into the ovary.
The second phase, laboratory, implies the application of complex technology, by which special systems are separated and purified by the corresponding cells, prepared and then activated.
The third stage involves inserting an active substance, derived from its own blood by a special treatment method, into the tissue of the ovary, outside the blood vessels.
– The effects relate to the growth of follicles and the production of egg cells in a spontaneous and stimulated cycle, as well as repairing the hormonal function of the ovaries. This allows for their fertilization and leads to more pregnancy. The first effects are expected in a month or two. For the next six months, the standard procedures of IVF in a natural, modified and stimulated cycle are carried out – emphasizes prof. Dr. Aleksandar Ljubić.