SEGOVA Stem Cell Therapy for Ovarian Rejuvenation

Are you struggling with infertility, early menopause, or ovarian failure?

The SEGOVA Ovarian Rejuvenation Program offers an innovative, natural fertility treatment to restore ovarian function and improve reproductive health—without synthetic hormones or medications.

Developed by Professor Aleksandar Ljubić and his team, SEGOVA combines stem cell therapy, growth factors, and ovarian tissue regeneration to naturally boost fertility and enhance hormonal balance.

Key Advantages of the SEGOVA Program:

100% Autologous & Safe – Utilizes the patient’s own stem cells and growth factors for natural ovarian restoration.
Restoration of Ovarian Function – Supports follicle development, hormone regulation, and reproductive potential.
Comprehensive, Personalized Treatment Plans – Incorporates tailored nutrition, metabolic, and fitness strategies for sustained ovarian health.

SEGOVA FRAMEWORK

How SEGOVA Ovarian Rejuvenation Works

The SEGOVA method is based on four essential pillars of ovarian regeneration therapy:

S – Stem Cell Therapy for Fertility
Uses your own stem cells to repair ovarian tissue, stimulate egg production, and restore hormonal balance.

E – Mitochondria & Energy Boosting
Optimizes ovarian cell function through biotechnological interventions and metabolic conditioning, including high-intensity interval training (HIIT).

G – Growth Factor Therapy (PPR for Ovarian Repair)
Employs platelet-rich plasma (PRP) and other growth factors derived from the patient’s own blood to rejuvenate ovarian cells and enhance fertility.

OVA – Ovarian In Vitro Activation (IVA Therapy)
An advanced technique aimed at reactivating dormant ovarian cells to promote follicular development and hormone production.

SEGOVA CANDIDATES

Who Can Benefit from Ovarian Rejuvenation?

Our natural fertility restoration treatment is ideal for:

Women with Premature Ovarian Failure (POF) or Primary Ovarian Insufficiency (POI)
Failed IVF cycles due to poor ovarian response or diminished egg quality
Early menopause & hormonal imbalances
Women experiencing age-related infertility.

SEGOVA LEVELS

Personalized Ovarian Rejuvenation

The SEGOVA Program offers three therapy levels—PRP-based, stem cell-based, and tissue-based—designed to restore ovarian function and enhance fertility based on individual patient needs.

BIO IVF (PRP-Based – Entry-Level Therapy)
A natural fertility-boosting therapy using platelet-rich plasma (PRP) to stimulate ovarian function, improve egg quality, and support hormone.

SEGO & DUAL SEGO (Stem Cell-Based – Intermediate-Level Therapy)
Employs autologous stem cells to regenerate ovarian tissue, enhance follicle and egg development, and restore hormonal balance.

SEGOVA & DUAL SEGOVA (Tissue-Based – Most Advanced Therapies)
The most powerful ovarian rejuvenation treatments, integrating stem cells, growth factors, and in vitro activation, d for optimal ovarian restoration and fertility enhancement.

Want more details on all therapy levels?

SEGOVA PROCEDURE

Comprehensive Ovarian Rejuvenation Therapy

First introduced in 2016, the SEGOVA procedure has continuously evolved to become a more advanced, precise, and effective ovarian rejuvenation therapy.

By 2022/2023, key innovations enhanced precision, efficiency, and patient recovery:

Minimally Invasive– Reduced hospital stay to 1–2 days
Enhanced Precision– Optimized tissue and stem cell transplantation for targeted ovarian repair
Improved Outcomes– Enhanced ovarian regeneration and reproductive success rates.

Key Elements:

Growth factors & bio-regenerative fibrin
Mesenchymal stem cell therapy
In vitro ovarian tissue activation
Personalized metabolic & physical optimization.

DUAL SEGOVA (DOS) PROCEDURE

Cutting Edge Ovarian Rejuvenation Therapy

Developed in 2024/2025, Dual SEGOVA (DOS – Dual Ovarian Stem-Cell Procedure) is the most advanced and absolutely unique ovarian rejuvenation therapy, combining two types of autologous stem cells—mesenchymal and hematopoietic—to maximize regenerative effects.

Key Advantages of Dual SEGOVA (DOS):

Enhanced ovarian restauration through the synergistic effects of multiple stem cell types
Increased stem cell yield, with cryopreservation options for future treatments.

SUPPORT AND FOLLOW UP

Ongoing Support for Fertility & Hormonal Health

Our commitment doesn’t end after treatment. We provide ongoing monitoring for up to two years, ensuring the best possible fertility outcomes:

Hormone & fertility tracking
Personalized supplement & nutrition plans
Metabolic & physical optimization strategies.

RESULTS

Why Choose SEGOVA?

Cutting-Edge Science & Innovation

Pioneering research led by Prof. Dr. Aleksandar Ljubić, a global leader in ovarian rejuvenation.
Exclusive, next-generation therapies using PRP, stem cells, and in vitro ovarian activation.

Personalized, Patient-Centered Care

Tailored treatment plans designed to align with each patient’s reproductive goals and ovarian health.
Comprehensive patient support, from initial consultation to post-treatment follow-up.

Seamless International Patient Experience

Full-service coordination, including travel, accommodation, paperwork, and medical scheduling and paperwork.
Multilingual support to ensure a smooth and stress-free treatment journey.

Proven Success & Long-Term Benefits

Effective fertility restoration for patients with premature ovarian failure, failed IVF cycles, and age-related infertility.
Minimally invasive procedures with shorter recovery times and minimally invasive, high precision.

Contact our team to learn more about how we can assist you.