SEGOVA OVARIAN IN VITRO ACTIVATION
The production of eggs – oogenesis, is dependent on proper genetic control. Hippo signalling pathway is essential for maintaining optimum organ size. It contains several negative growth regulators. The AKT signalling pathway has a key role in the initiation of follicle growth. The ovarian in vitro activation represents the autologous genetic treatment of the gonadal […]
SEGOVA GROWTH FACTOR PLRP THERAPY
In recent years, ovarian revitalization methods have been applied worldwide in order to improve the hormonal and reproductive conditions of the patient and thus their quality of life. In the literature, the most prevalent is PLRP method of rejuvenation. Growth factors are found in the granules and they play an important role in cell proliferation, […]
Quality of Life May 2020
The World Health Organization (WHO) defines the quality of life as “personal perception of one’s own life position, in the context of the cultural and value system in which individual lives and in relation to his goals, expectations, standards and interests.” Health-related quality of life describes subjective satisfaction with health status. 30 patients completed the […]
ENERGY MITOCHONDRIAL BOOSTING
It is well established that full competence of an oocyte (and thus-ovary) requires synchronous nuclear and cytoplasmic maturation. An oocyte contains numerous organelles and molecules that are required for development. Any mitochondrial malfunction, DNA mutation, defects in maternal mRNA storage, insufficient synthesis of proteins or untimely destruction of proteins, results in ovarian insufficiency. The impaired […]
STEM CELL THERAPY
Stem cell therapy (with stem cells obtained from the patient’s own body) aims to create new or incite existing non-differentiated ovarian stem cells – which are to be developed into new egg cells and hormone- producing cells. The ‘no new eggs’ doctrine has a long history. In 1951, the influential anatomist Solly Zuckerman, at the […]